Author

Ching-Lin Hsieh

The University of Texas at Austin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

Adelaide S. FulleriD· 1 shared Ajit R. RamamohaniD· 1 shared Alan WangiD· 1 shared Alison G. LeeiD· 1 shared Ashley L. MarcinkiewicziD· 1 shared Chelsea M. CrooksiD· 1 shared Dagnija TupiņaiD· 1 shared Dong Liang YuiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Adelaide S. FullerORCID

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2 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedApr 6, 2025

Mechanistic insights into structure-based design of a Lyme disease subunit vaccine

Kalvis Brangulis, Jill Malfetano, Ashley L. Marcinkiewicz…·Yi‐Pin Lin

This study demonstrates that structure-based mutagenesis of CspZ-YA improves antigen stability and immunogenicity, supporting its use in Lyme disease vaccine design.

6 citationstop 5%

mouseprotein structure

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 4, 2024

Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation

Madeline R. Sponholtz, Patrick O. Byrne, Alison G. Lee…·Jason S. McLellan

This paper describes the stabilization of HCMV gB in a prefusion-like conformation using structure-based design and shows similar neutralizing antibody titers against postfusion and prefusion forms.

37 citationstop 1%

humanprotein structure

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