Pharmacology & ToxicologybioRxiv
Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry
Yan Lin, Hyeim Jung, Christina A. Bulman…·Gilles Gasser
Simple derivatives of the well-known antifungal drug fluconazole were found to be highly effective in vivo against fungal infections and potent against parasitic nematodes causing lymphatic filariasis and soil-transmitted helminths.
DOI 10.1021/acs.jmedchem.3c01333