BiochemistryNature CommunicationsPeer-reviewed
Exposing the molecular heterogeneity of glycosylated biotherapeutics
Luis F. Schachner, Christopher Mullen, Wilson Phung…·Wendy N. Sandoval
This paper introduces a new method for analyzing glycoform heterogeneity in biotherapeutics using mass spectrometry and bioinformatics, showing its effectiveness in measuring proteoform diversity and correlating glycoform sub-populations with pharmacological properties.
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