Centromeric α-satellite DNA is a hotspot of genotoxic damage, incomplete repair, and cytoplasmic mislocalization
Azait Imtiaz, Mohammad Waseem, Hudson O'Neill…·Rafael Contreras-Galindo
The paper shows that centromeric α-satellite DNA is prone to genotoxic damage, incomplete repair, and cytoplasmic mislocalization, leading to chromosome instability and chromatin antigen exposure.