Author

Christopher J. Podracky

Broad Institute

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Genomics· 1

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Approach:experimental assay· 1 Organism:human· 1

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Aditya RaguramiD· 1 shared Andrew T. Nelson· 1 shared Andrew V. AnzaloneiD· 1 shared David R. LiuiD· 1 shared Jaron A. M. MerceriD· 1 shared Jonathan Ma LevyiD· 1 shared Luke W. KoblaniD· 1 shared Xin D. GaoiD· 1 shared

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2021-2021 · peak 1/yr

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Recent·Most cited

GenomicsbioRxivPreprintNov 1, 2021

Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinases

Andrew V. Anzalone, Xin D. Gao, Christopher J. Podracky…·David R. Liu

This paper introduces twin prime editing (twinPE) and its combination with site-specific recombinases to enable precise DNA deletion, replacement, integration, and inversion in human cells without double-strand breaks.

16 citations

humanexperimental assay

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