ImmunologymBioPeer-reviewed
Immunological correlates of protection mediated by a whole organism Cryptococcus neoformans vaccine deficient in chitosan
Charles A. Specht, Ruiying Wang, Lorena V. N. Oliveira…·Stuart M. Levitz
This paper identifies CD4+ T cells and their cytokines IFNγ, TNF, and IL-23 as critical for vaccine-mediated protection against Cryptococcus neoformans, with protection retained after vaccination even with CD4+ T cell depletion.
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