Plant BiologyProceedings of the National Academy of SciencesPeer-reviewed
A Fungal Natural Product that Inhibits Plant Cellulose Biosynthesis by disrupting Cellulose Synthase Complexes
Zhongshou Wu, Lu Liu, Wenyu Han…·Steven E. Jacobsen
This paper identifies a fungal natural product, MDD, as a novel cellulose biosynthesis inhibitor that targets CESA1 and disrupts cellulose synthase complexes, enabling the development of multi-drug resistant crop varieties.
DOI 10.1073/pnas.2602575123