Cell BiologyOncogenePeer-reviewed
Dual function of DOT1L suppresses tumor intrinsic immunogenicity in hepatocellular carcinoma
Siyuan Xu, Ruijie Gong, Songchen Liu…·Xianjiang Lan
The paper identifies DOT1L as a suppressor of tumor intrinsic immunogenicity using CRISPR screens and shows its inhibition enhances immune response in mice.