Author

Claire Francastel

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Claire FrancasteliD3 papers · Centre National de la Recherche Scientifique

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Guillaume VelascoiD· 2 shared Alexandra BenachiiD· 1 shared Alice JouneauiD· 1 shared Amandine JampyiD· 1 shared Andréa E. TijhuisiD· 1 shared Andrea ScelfoiD· 1 shared Anna ChipontiD· 1 shared Catalina Salinas‐LuypaertiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenomics

Guillaume VelascoORCID

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3 papers

Recent·Most cited

GenomicsHuman Molecular GeneticsPeer-reviewedNov 7, 2024

ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats

Giacomo Grillo, Ekaterina Boyarchuk, Seed Mihic…·Claire Francastel

This study identifies ZBTB24 as a transcription factor that regulates DNA methylation and expression of centromeric satellite repeats in human and mouse cells.

4 citations

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 22, 2023

Evidence of the ability of endocrine disrupting compounds to induce testicular germ cell cancer in humans.

Nour Nicolas, Delphine Moison, Amandine Jampy…·Marie-Justine Guerquin

This study shows that exposure to endocrine disrupting compounds during fetal development can lead to testicular germ cell cancer in adults.

DOI 10.1101/2023.12.22.573063

humanDNA methylation

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 4, 2023

Tunable DNMT1 degradation reveals cooperation of DNMT1 and DNMT3B in regulating DNA methylation dynamics and genome organization

Andrea Scelfo, Viviana Barra, Nezar A. Abdennur…·Daniele Fachinetti

This study uses tunable DNMT1 degradation to investigate DNA methylation dynamics and genome organization, revealing cooperative roles of DNMT1 and DNMT3B and their impact on heterochromatin and cell fitness.

5 citations

humanDNA methylation

𝕏 PostBluesky