Molecular BiologybioRxivPreprint
Transient inhibition of translation improves long-term cardiac function after ischemia/reperfusion by attenuating the inflammatory response
Christoph Hofmann, Adrian Serafin, Ole M. Schwerdt…·Mirko Völkers
This study shows that temporarily inhibiting protein translation after heart attack reduces inflammation and improves long-term heart function by targeting the mTORC1-4EBP1-eIF4F pathway.
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