Author

Clay Rouse

Duke University

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Ann Marie PendergastiD· 1 shared Ashley ColemoniD· 1 shared Tatiana PrioleauiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

Ann Marie PendergastORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 18, 2025

ABL Kinases Modulate EZH2 Phosphorylation and Signaling in Metastatic Triple Negative Breast Cancer

Ashley Colemon, Tatiana Prioleau, Clay Rouse, Ann Marie Pendergast

This study shows ABL kinases regulate EZH2 phosphorylation and function in TNBC, and their inhibition synergizes with EZH2 inhibitors to reduce tumor survival and metastasis.

2 citations

humanproteomics

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