Cell BiologyMolecular CellPeer-reviewed
'Off-pore' nucleoporins relocalize heterochromatic breaks through phase separation
Chiara Merigliano, Taehyun Ryu, Jakub Cibulka…·Irene Chiolo
The paper shows that Nup98 nucleoporins use phase separation to mobilize heterochromatic repair sites and exclude Rad51, promoting homologous recombination and genome integrity.
17 citations