Molecular BiologybioRxivPreprint
Natural Variation in HIV-1 Entry Kinetics Map to Specific Residues and Reveal an Interdependence Between Attachment and Fusion
Nicholas E. Webb, Colin Sevareid, Carolina Sanchez…·Grace M. Aldrovandi
The paper analyzes HIV-1 entry kinetics across 257 isolates, identifying single-residue determinants and showing cooperative sequential roles of co-receptor engagement and gp41 function in entry.
DOI 10.1101/2024.06.25.600587