NeuroscienceJournal of Cerebral Blood Flow & MetabolismPeer-reviewed
Malignant astrocyte swelling and impaired glutamate clearance drive the expansion of injurious spreading depolarization foci
Ákos Menyhárt, Rita Frank, Attila E. Farkas…·Eszter Farkas
The paper shows that brain edema from ischemic stroke impairs glutamate clearance, leading to widespread depolarization foci and neuronal death, suggesting osmotherapy could be beneficial.
46 citations