BioengineeringbioRxivPreprint
Intrathecal infusion of hypertonic fluid enables CSF Flow Enhancement (CFE) to facilitate nanoparticle delivery to the brain and spinal cord
Oluwatobi Helen Babayemi, Kha Uyen Dam, Chung-Fan Kuo…·Rachael W. Sirianni
This study demonstrates that intrathecal infusion of hypertonic fluid enhances cerebrospinal fluid flow, significantly improving nanoparticle delivery to the central nervous system.
DOI 10.64898/2026.06.29.735409