MicrobiologybioRxivPreprint
Trypanosoma brucei ribonuclease H2A is an essential enzyme that resolves R-loops associated with transcription initiation and antigenic variation
Emma Briggs, Kathryn Crouch, Leandro Lemgruber…·Richard McCulloch
This study shows that TbRH2A is essential for resolving R-loops and preventing DNA damage in T. brucei, with distinct roles in RNA Pol II and Pol I transcription.
DOI 10.1101/541300