ImmunologybioRxivPreprint
TyCHE enables time-resolved lineage tracing of heterogeneously-evolving populations
Jessie J. Fielding, Sherry Wu, Hunter J. Melton…·Kenneth B. Hoehn
TyCHE improves time-resolved lineage tracing by accounting for heterogeneous mutation rates, applied to memory B cells, germinal centers, gliomas, and bacterial infections.
DOI 10.1101/2025.10.21.683591