Author

Cynthia J. Meyer

The University of Texas Southwestern Medical Center

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Bioinformatics· 1

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein structure· 1

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Abeeb Abiodun YekeeniD· 1 shared Bruce A. PosneriD· 1 shared Kenneth D. WestoveriD· 1 shared Melissa K. McCoyiD· 1 shared

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BioinformaticsJournal of Chemical Information and ModelingPeer-reviewedFeb 7, 2026

A Computational Workflow for Structure-Guided Design of Potent and Selective Kinase Peptide Substrates

Abeeb Abiodun Yekeen, Cynthia J. Meyer, Melissa K. McCoy…·Kenneth D. Westover

This paper introduces Subtimizer, a computational pipeline for designing potent and selective kinase peptide substrates using AI tools, showing improved activity and selectivity in tested kinases.

1 citation

protein structuredeep learning

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