Cancer BiologybioRxivPreprint
Systemic immune dysfunction in cancer patients driven by IL6 and IL8 induction of an inhibitory receptor module in peripheral CD8+ T cells
A. Somasundaram, A. R. Cillo, C. Lampenfeld…·D. A. A. Vignali
This study identifies a systemic immune dysfunction in cancer patients driven by IL6 and IL8, leading to CD8+ T cell dysfunction and poor prognosis.
DOI 10.1101/2020.05.06.081471