Author

D. A. Johnston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

B. G. Sengers· 1 shared B. Grace· 1 shared B. P. Sharpe· 1 shared C. Tse· 1 shared D. Xu· 1 shared J. Harrington· 1 shared L. A. Nazlamova· 1 shared M. Browne· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

B. G. Sengers

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2 papers

Recent·Most cited

Patient-Derived Tumor Organoid and Fibroblast Assembloid Models for interrogation of the tumor microenvironment in Esophageal Adenocarcinoma

B. P. Sharpe, L. A. Nazlamova, C. Tse, D. A. Johnston, R. Blyth, O. J. Pickering, B. Grace, J. Harrington, R. Rajak, M. Rose-Zerilli, Z. S. Walters, T. J. Underwood

The paper develops assembloid models of esophageal adenocarcinoma using tumor organoids and fibroblasts to study the tumor microenvironment.

bioRxiv · Jan 2, 2024Cancer Biology

Geometric constraint of mechanosensing in bone marrow stromal cell cultures prevents stiffness-induced differentiation

M. L. Hernandez-Miranda, D. Xu, D. A. Johnston, M. Browne, R. B. Cook, B. G. Sengers, N. D. Evans

This study shows that in bone marrow stromal cells, matrix deformations and differentiation are influenced by ECM stiffness, geometry, and cell density, with high cell density reducing deformation differences between stiff and soft substrates.

bioRxiv · Oct 5, 2023 · PreprintBiophysics