Author

C. Tse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

T. J. Underwood· 2 shared Z. S. Walters· 2 shared A. Kelsey· 1 shared B. Grace· 1 shared B. P. Sharpe· 1 shared D. A. Johnston· 1 shared E. Aladowicz· 1 shared E. Gallicchio· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

T. J. Underwood

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Patient-Derived Tumor Organoid and Fibroblast Assembloid Models for interrogation of the tumor microenvironment in Esophageal Adenocarcinoma

B. P. Sharpe, L. A. Nazlamova, C. Tse, D. A. Johnston, R. Blyth, O. J. Pickering, B. Grace, J. Harrington, R. Rajak, M. Rose-Zerilli, Z. S. Walters, T. J. Underwood

The paper develops assembloid models of esophageal adenocarcinoma using tumor organoids and fibroblasts to study the tumor microenvironment.

bioRxiv · Jan 2, 2024Cancer Biology

Combination EZH2 inhibition and retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells

E. OBrien, C. Tse, I. Tracy, I. Reddin, J. Selfe, J. Gibson, W. Tapper, R. J. Pengelly, J. Gao, E. Aladowicz, G. Petts, K. Thway, S. Popov, A. Kelsey, T. J. Underwood, , Z. S. Walters

This study shows that combining EZH2 inhibition with retinoic acid treatment reduces RMS cell proliferation by inducing apoptosis or differentiation depending on the RMS subtype.

bioRxiv · Jun 12, 2023 · PreprintCancer Biology

Exploring the Free Energy Landscape and Thermodynamics of Protein-Protein AssociationAssociation: HIV-1 Integrase Multimerization Induced by an Allosteric Inhibitor

N. Deng, C. Tse, L. Wickstrom, M. Kvaratskhelia, E. Gallicchio, R. Levy

This paper investigates the thermodynamics and free energy landscape of HIV-1 integrase multimerization induced by an allosteric inhibitor, revealing short-range interactions and enthalpy-driven binding.

bioRxiv · Jun 29, 2020Biophysics