Author

D. Amsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Organism:human· 4 Assay:proteomics· 4 Approach:experimental assay· 3 Assay:flow cytometry· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. B. Haanen· 2 shared K. Monkhorst· 2 shared M. C. Wolkers· 2 shared M. M. van Loenen· 2 shared R. M. Spaapen· 2 shared A. Bex· 1 shared A. Guislain· 1 shared A. Khmelevskaya· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

J. B. Haanen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Public T-Cell Receptors (TCRs) Revisited by Analysis of the Magnitude of Identical and Highly-Similar TCRs in Virus-Specific T-Cell Repertoires of Healthy Individuals

W. Huisman, L. Hageman, D. A. T. Leboux, A. Khmelevskaya, G. A. Efimov, M. C. J. Roex, D. Amsen, J. H. F. Falkenburg, I. Jedema

The paper quantifies public TCR sequences in virus-specific T-cell repertoires of healthy individuals, finding high prevalence and frequency of identical and highly-similar TCRs.

bioRxiv · Nov 29, 2021Immunology

Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4+ regulatory T cells

M. Mensink, E. Schrama, E. Cuadrado, M. van den Biggelaar, D. Amsen, J. Borst, S. de Kivit

The paper uses proteomics to compare TGF-β-induced iTreg cells with thymus-derived tTreg and Tconv cells, finding iTreg cells have distinct protein expression patterns and lack key Treg signatures.

bioRxiv · Oct 30, 2021Immunology

T cells expanded from renal cell carcinoma are tumor-reactive but fail to produce IFN-γ, TNF-α or IL-2

S. D. van Asten, R. d. Groot, M. M. van Loenen, J. d. Jong, K. Monkhorst, J. B. Haanen, D. Amsen, A. Bex, R. M. Spaapen, M. C. Wolkers

The paper examines TILs from RCC patients, finding that while some are tumor-reactive, they fail to produce key cytokines in response to autologous tumors.

bioRxiv · May 17, 2020 · PreprintImmunology

Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile

R. de Groot, M. M. van Loenen, A. Guislain, B. P. Nicolet, J. J. Freen-van Heeren, O. Verhagen, M. M. van den Heuvel, J. de Jong, P. Burger, E. van der Schoot, R. M. Spaapen, D. Amsen, J. B. Haanen, K. Monkhorst, K. J. Hartemink, M. C. Wolkers

The paper isolates and expands tumor-reactive T cells from NSCLC tumors, finding that polyfunctional T cells correlate with immune-engaged T cell profiles and tumor reactivity.

bioRxiv · Jun 8, 2019Immunology