Author

D. Avram

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Kwiatkowski· 2 shared B. G. Keselowsky· 2 shared E. Y. Helm· 2 shared A. N. Zuniga· 1 shared A. Restuccia· 1 shared A. Riva· 1 shared A. Wanchoo· 1 shared B. D. Partain· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioengineering

A. J. Kwiatkowski

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer

Y. Feng, R. C. Newsome, T. Robinson, R. L. Bowman, A. N. Zuniga, K. N. Hall, C. M. Berntsen, D. E. Shabashvili, K. I. Krajcik, C. Gunaratne, Z. J. Zaroogian, K. Venugopal, H. L. Casellas Roman, R. L. Levine, W. K. Chatila, , O. A. Guryanova

This study shows that hematopoietic Dnmt3a haploinsufficiency worsens colitis-associated colon cancer by promoting angiogenesis, which can be targeted with axitinib.

bioRxiv · Dec 30, 2022 · PreprintCancer Biology

Treatment with an Antigen-Specific Dual Microparticle System Reverses Advanced Multiple Sclerosis in Mice

A. J. Kwiatkowski, E. Y. Helm, J. M. Stewart, T. T. Drashansky, J. J. Cho, D. Avram, B. G. Keselowsky

This paper demonstrates that an antigen-specific dual microparticle treatment reverses hind limb paralysis in advanced EAE mice by reducing antigen presentation in APCs.

bioRxiv · Mar 25, 2022Bioengineering

Galectin-anchored indoleamine 2,3-dioxygenase suppresses local inflammation

E. Bracho-Sanchez, F. Rocha, S. K. Bedingfield, B. D. Partain, M. A. Brusko, J. M. Colazo, M. M. Fettis, S. A. Farhadi, E. Y. Helm, K. Koenders, A. J. Kwiatkowski, S. L. Macias, A. Restuccia, A. Wanchoo, D. Avram, , B. G. Keselowsky

This paper develops a fusion protein IDO-Gal3 that anchors immunosuppressive enzymes to tissues, effectively suppressing local inflammation in multiple disease models.

bioRxiv · May 7, 2021 · PreprintBioengineering