Cancer BiologybioRxivPreprint
HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia
S. Agrawal Singh, J. Bagri, G. Giotopoulos…·B. J. P. Huntly
This study identifies a repressive HOXA9-SAFB complex in AML that maintains disease by inhibiting differentiation and apoptosis, suggesting therapeutic targets.
DOI 10.1101/2022.10.12.511919