H. Yun

This study identifies locus-specific DNA methylation defects at bivalent chromatin as a common feature in growth disorders caused by DNMT3A or NSD1 mutations.

The paper describes a new Cambrian sponge fossil with a long stalk, indicating an early adaptation to low-oxygen environments and a deep origin of stalk-bearing morphology in hexactinellid sponges.

This study identifies a repressive HOXA9-SAFB complex in AML that maintains disease by inhibiting differentiation and apoptosis, suggesting therapeutic targets.

This paper identifies and characterizes a novel oxidase gene cmO in Sphingomonadaceae that mediates chloramphenicol and thiamphenicol resistance through oxidative inactivation.

This study identifies p300-mediated compensatory transcriptional programs that drive acute resistance to BET inhibitors in AML and suggests sequential BET- and p300-inhibition as a therapeutic strategy.

This study shows Aspergillus tabacinus LZ-M can degrade acid red 73 anaerobically through a self-redox mechanism, mineralizing it to CO2 with a 90.28% decolorization rate in 5 days.

The paper withdraws due to the need for further experiments to validate conclusions about Bfl-1 and HDAC inhibition in diffuse large B cell lymphoma.

The paper identifies key immune genes and develops a transcriptional deviance score to predict immune checkpoint inhibitor responses in melanoma patients.

The paper investigates how mutations synergize to alter chromatin accessibility, enhancer landscapes, and 3D DNA topology in leukemia induction using a murine model.

This study compares host-related factors and environmental factors in shaping gut microbiota using fecal samples from naval trainees and healthy individuals, finding host factors more influential.