Interleukin-1α and Leukemia Inhibitory Factor Promote Extramedullary Hematopoiesis
D. Barisas, M. Kim, M. Subramanian, A. U. Kabir, K. Krchma, J. Wu, B. Zinselmeyer, C. Stewart, K. Choi
This study identifies IL-1 and LIF as factors promoting EMH by activating splenic niche cells and inducing an inflammatory gene signature in HSPCs.
bioRxiv · Jul 7, 2022 · PreprintImmunology