Author

D. Beste

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

K. Borah· 2 shared A. Theorell· 1 shared B. S. Hall· 1 shared C. Moller-Levet· 1 shared F. Sorgeloos· 1 shared H. Wu· 1 shared I. G. Goodfellow· 1 shared J. Lu· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

K. Borah

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2 papers

Recent·Most cited

Murine Norovirus infection results in anti-inflammatory response downstream of amino acids depletion in macrophages

M. Brocard, J. Lu, B. S. Hall, K. Borah, C. Moller-Levet, F. Sorgeloos, D. Beste, I. G. Goodfellow, N. Locker

This study shows that murine norovirus induces metabolic stress in macrophages, leading to anti-inflammatory responses through amino acid depletion and GCN2/ATF2 signaling, rather than a typical innate immune response.

bioRxiv · Apr 22, 2021Microbiology

A mixed nitrogen diet and compartmentalized utilization for Mycobacterium tuberculosis replicating in host cells: results of a systems-based analysis

K. Borah, M. Beyss, A. Theorell, H. Wu, P. Basu, T. Mendum, K. Noh, D. Beste, J. McFadden

This study investigates nitrogen metabolism in intracellular Mycobacterium tuberculosis using a systems-based approach, revealing compartmentalized utilization of host-derived nitrogen sources.

bioRxiv · Feb 6, 2019 · PreprintMicrobiology