Author

D. Bolon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:virus· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. A. Schiffer· 2 shared A. M. Shaqra· 1 shared C. Xu· 1 shared D. Dovala· 1 shared G. Nachum· 1 shared J. M. Flynn· 1 shared J. P. Wang· 1 shared K. Song· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

C. A. Schiffer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Contributions of hyperactive mutations in Mpro from SARS-CoV-2 to drug resistance

J. M. Flynn, S. N. Zvornicanin, A. M. Shaqra, N. Kurt Yilmaz, S. Moquin, D. Dovala, C. A. Schiffer, D. Bolon

This study identifies hyperactive mutations in SARS-CoV-2 Mpro that increase enzyme activity and contribute to drug resistance, finding them more prevalent than binding-reducing mutations.

bioRxiv · Sep 28, 2023 · PreprintBiochemistry

Sequence dependencies and biophysical features both govern cleavage of diverse cut-sites by HIV protease

N. Samant, G. Nachum, T. Tsepal, D. Bolon

bioRxiv · Apr 18, 2022Biochemistry

Quantitative Structural Analysis of Influenza Virus by Cryo-electron Tomography and Convolutional Neural Networks

Q. Y. Huang, K. Song, C. Xu, D. Bolon, J. P. Wang, R. W. Finberg, C. A. Schiffer, M. Somasundaran

This paper develops a cryoET processing pipeline using CNNs to characterize the morphology and structure of influenza viruses, improving analysis throughput and enabling subtomogram averaging of glycoproteins.

bioRxiv · Dec 9, 2021Microbiology