N. Kurt Yilmaz

The paper determines inhibitor-bound crystal structures of main proteases from delta and gamma coronaviruses to inform structure-based inhibitor design.

This study defines the substrate envelope of SARS-CoV-2 main protease using cocrystal structures to identify vulnerable sites that may lead to drug resistance.

This study identifies an IgA monoclonal antibody that blocks SARS-CoV-2 Spike-ACE2 interaction and provides mucosal immunity.

This study identifies the structural basis for APOBEC3B's lower catalytic activity and DNA binding through molecular modeling and mutational analysis.

This study identifies the APOBEC3A ssDNA binding motif and shows that substrate affinity is influenced by DNA structure, not just sequence, leading to a new model for its sequence preference.