Author

D. Brun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:protein structure prediction· 2 Organism:Arabidopsis· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

F. A. Rey· 3 shared M. Backovic· 3 shared A. Gessain· 2 shared A. Haouz· 2 shared F. Buseyne· 2 shared I. Fernandez· 2 shared R. Pederzoli· 2 shared Y. Coquin· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

F. A. Rey

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses

I. Fernandez, F. Bontems, D. Brun, Y. Coquin, C. A. Goverde, B. E. Correia, A. Gessain, F. Buseyne, F. A. Rey, M. Backovic

The paper reports cryo-EM structures of foamy virus Env in pre- and post-fusion states, revealing structural similarity to paramyxovirus F proteins and suggesting an evolutionary link.

bioRxiv · Feb 9, 2024Microbiology

The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells

I. Fernandez, L. Tofdal Dynesen, Y. Coquin, R. Pederzoli, D. Brun, A. Haouz, A. Gessain, F. A. Rey, F. Buseyne, M. Backovic

The paper determines the X-ray structure of a simian Foamy Virus receptor binding domain, revealing its fold and key residues involved in heparan sulfate interaction.

bioRxiv · Oct 4, 2022Microbiology

Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling

T. L. Light, D. Brun, P. Guardado-Calvo, R. Pederzoli, A. Haouz, F. Neipel, F. A. Rey, K. Hristova, M. Backovic

This study identifies how HHV-8 uses molecular mimicry of ephrin ligands to bind EphA2, triggering signaling that facilitates viral entry and cytoskeleton remodeling.

bioRxiv · Mar 26, 2021Microbiology

The Arabidopsis F-box protein FBW2 degrades AGO1 to avoid spurious loading of illegitimate small RNA

T. Hacquard, M. Clavel, P. Baldrich, E. Lechner, I. Perez-Salamo, M. Schepetilnikov, B. Derrien, M. Dubois, P. Hammann, L. Kuhn, D. Brun, N. Bouteiller, H. Vaucheret, B. Meyers, P. Genschik

This study shows that FBW2 degrades AGO1 to prevent off-target RNA silencing by avoiding illegitimate small RNA loading.

bioRxiv · Mar 24, 2021 · PreprintCell Biology