P. Hammann

Identification of new proviral and antiviral factors through the study of the Dicer-2 interactome in vivo during viral infection in Drosophila melanogaster

Arabidopsis AGO1 N-terminal Poly-Q domain promotes phase separation and association with stress granules during heat stress

This study shows that AGO1's Poly-Q domain enables phase separation and association with stress granules during heat stress in Arabidopsis, protecting AGO1 function without affecting small RNA activity.

DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection

This study identifies DDX5 as a pro-viral host factor for Sindbis virus infection, showing its interaction with viral RNA and capsid protein, and demonstrating that its depletion reduces viral replication.

Cell type-specific control of secondary cell wall formation by Musashi-type translational regulators in Arabidopsis

This study identifies MSIL2 and MSIL4 as cell type-specific regulators of secondary cell wall formation in Arabidopsis by controlling mRNA translation and biosynthetic gene expression.

FRIENDLY (FMT) is an RNA binding protein associated with cytosolic ribosomes at the mitochondrial surface

The paper identifies FMT as an RNA-binding protein that localizes to mitochondrial surfaces and is involved in mRNA localization and translation, with knockdown affecting seedling development and mitochondrial function.

A NYN domain protein directly interacts with DCP1 and is required for phyllotactic pattern in Arabidopsis.

DNE1, a NYN domain protein interacts with DCP1 and, together with DCP2, specify phyllotactic patterns in Arabidopsis.

Human DICER helicase domain recruits PKR and modulates its antiviral activity

The paper shows that DICER's helicase domain recruits PKR and modulates its antiviral activity during alphavirus infection.

The Arabidopsis F-box protein FBW2 degrades AGO1 to avoid spurious loading of illegitimate small RNA

This study shows that FBW2 degrades AGO1 to prevent off-target RNA silencing by avoiding illegitimate small RNA loading.

Proteomics-based determination of double stranded RNA interactome reveals known and new factors involved in Sindbis virus infection

This study identifies SFPQ as a new proviral factor involved in Sindbis virus infection by characterizing the dsRNA interactome using anti-dsRNA immunoprecipitation and mass spectrometry.

Cex1 is a new component of the COPI Golgi-to-vacuole intracellular trafficking machinery

The paper identifies Cex1 as a COPI complex component involved in Golgi-to-vacuole trafficking in yeast, challenging its previously proposed role in nuclear tRNA channeling.