Author

D. Chauhan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

S. R. Shames· 2 shared A. Aktas-Samur· 1 shared A. G. Salberg· 1 shared A. Gulla· 1 shared A. L. Froehlich· 1 shared A. M. Joseph· 1 shared A. Neri· 1 shared C. A. Stafford· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

S. R. Shames

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Intrabacterial regulation of a cytotoxic effector by its cognate metaeffector promotes Legionella pneumophila virulence

D. Chauhan, A. M. Joseph, S. R. Shames

This study shows that MesI, a metaeffector of Legionella pneumophila, regulates the cytotoxic effector SidI within the bacterium, which is critical for virulence.

bioRxiv · Jun 12, 2022Microbiology

Effector-mediated subversion of proteasome activator (PA)28αβ enhances host defense against Legionella pneumophila under inflammatory and oxidative stress conditions

T. Ngwaga, D. Chauhan, A. G. Salberg, S. R. Shames

This study shows that the L. pneumophila effector LegC4 enhances host defense against the pathogen under inflammatory and oxidative stress by subverting the host proteasome activator PA28β.

bioRxiv · Dec 27, 2021 · PreprintMicrobiology

Long Noncoding RNA RROL Provides Chromatin Scaffold for MYC-WDR82 Interaction to Impact Lipid Metabolism and Tumor Cell Growth in Multiple Myeloma

E. Morelli, M. Fulciniti, M. K. Samur, C. F. Ribeiro, L. Wert-Lamas, J. E. Henninger, A. Gulla, A. Aktas-Samur, K. Todoerti, S. Talluri, W. D. Park, C. Federico, F. Scionti, N. Amodio, G. Bianchi, , N. C. Munshi

This study identifies RROL as a therapeutically actionable lncRNA in multiple myeloma that supports tumor growth through chromatin scaffolding of MYC-WDR82 interaction.

bioRxiv · Dec 8, 2021 · PreprintCancer Biology

Priming enables a NEK7-independent route of NLRP3 activation

N. A. Schmacke, M. M. Gaidt, I. Szymanska, F. O'Duill, C. A. Stafford, D. Chauhan, A. L. Froehlich, D. Nagl, F. Pinci, J. L. Schmid-Burgk, V. Hornung

This study shows that NEK7 is not required for NLRP3 activation in human and murine cells under pro-inflammatory conditions when TAK1-dependent priming is active.

bioRxiv · Oct 9, 2019 · PreprintImmunology