Author

G. Bianchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Bioengineering· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

I. Pertici· 2 shared P. Bianco· 2 shared A. Aktas-Samur· 1 shared A. Gulla· 1 shared A. Luraghi· 1 shared A. Neri· 1 shared A. V. Kashchuk· 1 shared A. Zaza· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

I. Pertici

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Long Noncoding RNA RROL Provides Chromatin Scaffold for MYC-WDR82 Interaction to Impact Lipid Metabolism and Tumor Cell Growth in Multiple Myeloma

E. Morelli, M. Fulciniti, M. K. Samur, C. F. Ribeiro, L. Wert-Lamas, J. E. Henninger, A. Gulla, A. Aktas-Samur, K. Todoerti, S. Talluri, W. D. Park, C. Federico, F. Scionti, N. Amodio, G. Bianchi, , N. C. Munshi

This study identifies RROL as a therapeutically actionable lncRNA in multiple myeloma that supports tumor growth through chromatin scaffolding of MYC-WDR82 interaction.

bioRxiv · Dec 8, 2021 · PreprintCancer Biology

Istaroxime metabolite PST3093 selectively stimulates SERCA2a and reverses disease-induced changes in cardiac function

M. Arici, M. Ferrandi, P. Barassi, S.-C. Hsu, E. Torre, A. Luraghi, C. Ronchi, G.-J. Chang, F. Peri, P. Ferrari, G. Bianchi, M. Rocchetti, A. Zaza

This paper investigates PST3093, a metabolite of istaroxime, showing it selectively stimulates SERCA2a and improves cardiac function in a rat model of diabetic cardiomyopathy.

bioRxiv · Aug 17, 2021Pharmacology & Toxicology

A myosin II-based nanomachine devised for the study of Ca2+-dependent mechanisms of muscle regulation

I. Pertici, G. Bianchi, L. Bongini, V. Lombardi, P. Bianco

This paper describes a synthetic nanomachine using myosin II and actin to study Ca2+-dependent muscle regulation mechanisms, showing consistent power output across Ca2+ concentrations.

bioRxiv · Sep 5, 2020Biophysics

α-catenin switches between a slip and an asymmetric catch bond with F-actin to cooperatively regulate cell junction fluidity

C. Arbore, M. Sergides, L. Gardini, G. Bianchi, A. V. Kashchuk, I. Pertici, P. Bianco, F. S. Pavone, M. Capitanio

This study shows that -catenin forms different types of bonds with F-actin depending on its dimerization state and applied force, affecting cell junction fluidity.

bioRxiv · Apr 15, 2020Biophysics

A numerical study about the flight of the dragonfly: 2D gliding and 3D hovering regimes

L. Benedetti, G. Bianchi, S. Cinquemani, M. Belloli

This paper analyzes dragonfly flight regimes through CFD simulations and BEM theory, showing good agreement between simulated and experimental data for gliding and hovering.

bioRxiv · Mar 6, 2020Bioengineering