Long Noncoding RNA RROL Provides Chromatin Scaffold for MYC-WDR82 Interaction to Impact Lipid Metabolism and Tumor Cell Growth in Multiple Myeloma
E. Morelli, M. Fulciniti, M. K. Samur, C. F. Ribeiro, L. Wert-Lamas, J. E. Henninger, A. Gulla, A. Aktas-Samur, K. Todoerti, S. Talluri, W. D. Park, C. Federico, F. Scionti, N. Amodio, G. Bianchi, , N. C. Munshi
This study identifies RROL as a therapeutically actionable lncRNA in multiple myeloma that supports tumor growth through chromatin scaffolding of MYC-WDR82 interaction.
bioRxiv · Dec 8, 2021 · PreprintCancer Biology