Author

D. Chowell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Charap· 1 shared A. M. Farkas· 1 shared A. O. Kamphorst· 1 shared B. Lee· 1 shared B. Salome· 1 shared C. Hammer· 1 shared C. Valero· 1 shared D. Geanon· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

A. Charap

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Robust prediction of patient outcomes with immune checkpoint blockade therapy for cancer using common clinical, pathologic, and genomic features

T.-G. Chang, Y. Cao, H. Sfreddo, S. R. Dhruba, S.-H. Lee, C. Valero, S.-K. Yoo, D. Chowell, L. G. T. Morris, E. Ruppin

This study develops a logistic regression model to predict immune checkpoint blockade response and survival in cancer patients using common clinical and genomic features.

bioRxiv · Jul 4, 2023 · PreprintCancer Biology

NKG2A and HLA-E define a novel alternative immune checkpoint axis in bladder cancer

B. Salome, J. P. Sfakianos, J. Daza, A. Charap, C. Hammer, R. Banchereau, A. M. Farkas, D. Geanon, G. Kelly, R. M. de Real, B. Lee, K. G. Beaumont, S. Shroff, Y. S. A. Wang, Y.-C. Wang, , Mariath

This study identifies NKG2A and HLA-E as an alternative immune checkpoint axis in bladder cancer, showing NKG2A+ CD8 T cells can bypass HLA-ABC loss through TCR-independent cytotoxicity.

bioRxiv · Mar 4, 2022 · PreprintImmunology