Author

Y.-C. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 2 Cancer Biology· 2 Cell Biology· 2 Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Research Focus:host-pathogen & immune response· 7 Research Focus:cell type annotation· 4 Organism:mouse· 4 Assay:proteomics· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

C.-C. Liao· 2 shared C.-P. Sun· 2 shared D. K. Ann· 2 shared J.-T. Jan· 2 shared Y. Qi· 2 shared Y.-H. Chen· 2 shared Y.-L. Lin· 2 shared Y.-S. Lin· 2 shared

Activity by Year

2020-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

C.-C. Liao

Mutual co-authors in cluster

Author profile →

13 papers

Recent·Most cited

Comparison of Multiple Carbapenemase Tests Based on an Unbiased Colony Selection Method

H.-Y. Wang, Y.-J. Tseng, W.-Y. Lin, Y.-C. Wang, T.-W. Lin, J.-F. Hsu, M. Y.-C. Wu, C.-H. Wu, S. Kalpana, J.-J. Lu

This study compares carbapenemase tests using an unbiased colony selection method, finding improved detection and highlighting performance discrepancies among tests.

Biomedicines · Sep 20, 2024Peer-reviewedMicrobiology

Temporal Transcriptome Analysis Uncovers Regulatory Modules Programming Embryo Development from Embryonic Morphogenesis to Post-Germination

Y.-C. Wang, W.-H. Hsieh, C.-J. Huang, Y.-T. Jhan, J. Zhan, C.-C. Chang, T.-F. Hsieh, J.-Y. Lin

The paper profiles soybean seed embryo transcriptomes across development to identify gene functions and regulatory networks involved in reserve accumulation and germination.

bioRxiv · Dec 26, 2023 · PreprintPlant Biology

New insights into functional divergence and adaptive evolution of uncultured bacteria in anammox community by complete genome-centric analysis

Y.-C. Wang, Y. Mao, H.-M. Fu, J. Wang, X. Weng, Z.-H. Liu, X.-W. Xu, P. Yan, F. Fang, J.-S. Guo, Y. Shen, Y.-P. Chen

The paper uses long-read sequencing to obtain complete metagenome-assembled genomes of anammox bacteria, revealing functional divergence and adaptive evolution through horizontal gene transfer and mobile genetic elements.

bioRxiv · Aug 15, 2023Microbiology

Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

Y.-C. Wang, A. A. Kelso, A. Karamafrooz, Y.-H. Chen, W.-K. Chen, C.-T. Cheng, Y. Qi, L. Gu, L. Malkas, H.-J. Kung, G.-L. Moldovan, A. Ciccia, J. M. Stark, D. K. Ann

bioRxiv · Jan 31, 2023 · PreprintCancer Biology

Simultaneous transcriptome and proteome profiling in a single mouse oocyte with a deep single-cell multi-omics approach

Y.-R. Jiang, L. Zhu, L.-R. Cao, Q. Wu, J.-B. Chen, Y. Wang, J. Wu, T.-Y. Zhang, Z.-L. Wang, Z.-Y. Guan, Q.-Q. Xu, Q.-X. Fan, S.-W. Shi, H.-F. Wang, J.-Z. Pan, , Q. Fang

The paper develops a single-cell multi-omics platform to simultaneously profile transcriptome and proteome in mouse oocytes, revealing transcriptome-proteome heterogeneity and identifying maturational signatures.

bioRxiv · Aug 17, 2022Cell Biology

Glutamine is essential for overcoming theimmunosuppressive microenvironment in malignant salivary gland tumors

S. Cao, Y.-W. Hung, Y.-C. Wang, Y. hung, Y. Qi, C. Ouyang, X. Zhong, W. Hu, A. Coblentz, E. Maghami, Z. Sun, H. H. Lin, D. K. Ann

This study shows that dietary glutamine supplementation enhances antitumor immunity by altering the tumor microenvironment in mice with malignant salivary gland tumors.

bioRxiv · Apr 29, 2022 · PreprintCancer Biology

Parkinson mutations in DNAJC6 cause lipid defects and neurodegeneration that are rescued by Synj1

J. Jacquemyn, S. Kuenen, J. Swerts, B. Pavie, V. Vijayan, A. Kilic, D. Chabot, Y.-C. Wang, N. Schoovaerts, P. Verstreken

This study shows that Parkinson's mutations in DNAJC6 cause lipid defects and neurodegeneration in Drosophila, which are rescued by overexpressing Synj1.

bioRxiv · Apr 27, 2022 · PreprintCell Biology

NKG2A and HLA-E define a novel alternative immune checkpoint axis in bladder cancer

B. Salome, J. P. Sfakianos, J. Daza, A. Charap, C. Hammer, R. Banchereau, A. M. Farkas, D. Geanon, G. Kelly, R. M. de Real, B. Lee, K. G. Beaumont, S. Shroff, Y. S. A. Wang, Y.-C. Wang, , Mariath

This study identifies NKG2A and HLA-E as an alternative immune checkpoint axis in bladder cancer, showing NKG2A+ CD8 T cells can bypass HLA-ABC loss through TCR-independent cytotoxicity.

bioRxiv · Mar 4, 2022 · PreprintImmunology

Chlamydomonas mutant hpm91 lacking PGR5 is a scalable and valuable strain for algal hydrogen (H2) production

P. Liu, D.-M. Ye, M. Chen, J. Zhang, X.-H. Huang, L.-L. Shen, K.-K. Xia, X.-J. Xu, Y.-C. Xu, Y.-L. Guo, Y.-C. Wang, F. Huang

The paper identifies hpm91, a Chlamydomonas mutant with high hydrogen production, as scalable and robust for large-scale algal H2 photoproduction.

bioRxiv · Feb 23, 2022 · PreprintBiochemistry

Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Syrian hamsters

R. Kulkarni, W.-C. Chen, Y. Lee, C.-F. Kao, S.-L. Hu, H.-H. Ma, J.-T. Jan, C.-C. Liao, J.-J. Liang, H.-Y. Ko, C.-P. Sun, Y.-S. Lin, Y.-C. Wang, S.-C. Wei, Y.-L. Lin, , W. Chang

This study evaluates two vaccinia virus-based SARS-CoV-2 vaccines in mice and hamsters, showing they induce neutralizing antibodies and protect against infection.

bioRxiv · Aug 3, 2021Immunology

Autonomous epithelial folding induced by an intracellular mechano-polarity feedback loop

F.-L. Wen, C. W. Kwan, Y.-C. Wang, T. Shibata

The paper develops a mechano-biochemical model to explain autonomous epithelial folding in Drosophila embryos through a feedback loop between cell mechanics and polarity.

bioRxiv · Feb 10, 2021Biophysics

CpG-adjuvanted stable prefusion SARS-CoV-2 spike protein protected hamsters from SARS-CoV-2 challenge

C.-E. Lien, Y.-J. Lin, C. Chen, W.-C. Lian, T.-Y. Kuo, J. D. Campbell, P. Traquina, M.-Y. Lin, L. T. C. Liu, Y.-S. Chuang, H.-Y. Ku, C.-C. Liao, Y.-H. Chen, J.-T. Jan, C.-P. Sun, , Y.-L. Lin

This study shows that CpG-adjuvanted S-2P vaccine protected hamsters from SARS-CoV-2 infection by inducing high neutralizing antibodies and reducing viral load.

bioRxiv · Jan 7, 2021Microbiology

Inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 main protease by tafenoquine in vitro

Y. Chen, W.-H. Yang, L.-M. Huang, Y.-C. Wang, C.-S. Yang, Y.-L. Liu, M.-H. Hou, C.-L. Tsai, Y.-Z. Chou, B.-Y. Huang, C.-F. Hung, Y.-L. Hung, J.-S. Chen, Y.-P. Chiang, D.-Y. Cho, , M.-C. Hung

This study identifies tafenoquine as an inhibitor of SARS-CoV-2 main protease, showing it reduces protease activity and inhibits viral infection in vitro.

bioRxiv · Aug 14, 2020 · PreprintBiochemistry