Tyrosine phosphorylation of ACLY regulates lipid metabolism and oncogenesis in ALK positive Anaplastic Large Cell Lymphoma
J. Basappa, M. ElAzzouny, D. Rolland, A. Sahasrabuddhe, K. Ma, G. Bazilevsky, S. R. Hwang, V. Basrur, K. Conlon, N. Bailey, J. Frederiksen, S. Schnell, Y. Zhou, D. Cookmeyer, J. Pawlicki, , M. Lim
This study identifies tyrosine phosphorylation of ACLY at Y682 as a regulatory mechanism linked to lipid metabolism and oncogenesis in ALK-positive ALCL.
bioRxiv · Jan 20, 2020 · PreprintCancer Biology