K. Ma

Leeches Predate on Fast-Escaping and Entangling Blackworms by Spiral Entombment

This study describes how Helobdella leeches capture fast-escaping blackworms using a spiral entombment strategy, highlighting predator-prey dynamics in freshwater ecosystems.

Multi-dimensionality of tree communities structure host-parasitoid networks and their phylogenetic composition

The paper examines how tree diversity and canopy cover affect host-parasitoid community composition and interaction networks in a subtropical tree biodiversity experiment.

Nicotine Ameliorates α-synuclein Pre-formed Fibril-Induced Behavioral Deficits and Pathological Features in Mice

This study shows nicotine reduces α-synuclein pathology and behavioral deficits in mice induced by human α-synuclein pre-formed fibrils.

Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation

This study shows that monocyte-to-macrophage differentiation and redox changes influence HIV latency differently in cell types, with macrophages being more responsive to redox modulators.

MolPad: An R-Shiny Package for Cluster Co-Expression Analysis in Longitudinal Microbiomics

MolPad is an R-Shiny package that provides an interactive dashboard for analyzing longitudinal microbiome co-expression patterns through cluster-based network visualization and data integration.

A specific innate immune response silences the virulence of Pseudomonas aeruginosa in a latent infection model in the Drosophila melanogaster host

This study shows that a latent Pseudomonas aeruginosa infection in Drosophila melanogaster is silenced by an innate immune response, specifically melanization, and provides protection against secondary infections.

Anti-adipogenic properties of clock activator chlorhexidine and a new derivative

This study identifies chlorhexidine and its derivative CM002 as clock activators with anti-adipogenic properties, showing they inhibit adipogenesis via Wnt pathway activation.

The clinical, genomic, and transcriptomic landscape of BRAF mutant cancers

This paper analyzes the clinical, genomic, and transcriptomic features of BRAF mutant cancers across multiple tumor types and identifies demographic and molecular differences between BRAF mutation classes.

Tree diversity increases forest temperature buffering

This study shows that higher tree species diversity enhances forest temperature buffering across multiple time scales, mediated by canopy density and structural diversity.

CRISPR-Cas12a-Based Rapid and Sensitive Detection of rpoBL378R in Mycobacterium tuberculosis

This paper develops a CRISPR-Cas12a-based detection system to identify the rpoBL378R mutation in Mycobacterium tuberculosis, showing high specificity and sensitivity for drug-resistant strains.

Latitudinal scaling of aggregation with abundance and its consequences for coexistence in species rich forests

The paper examines latitudinal patterns in species aggregation and abundance, showing how these patterns affect coexistence in forests and introduces a framework to model their impact on extinction risk.

Transcription repression of Cry2 via Per2 interaction promotes adipogenesis

This study identifies Cry2's role in adipogenesis through its interaction with Per2, showing that repression of Wnt signaling promotes adipocyte development.

The clock-modulatory activity of Nobiletin suppresses adipogenesis via Wnt signaling

This study shows Nobiletin suppresses adipogenesis by enhancing the circadian clock and activating Wnt signaling, leading to reduced fat mass and body weight in mice.

The more synthetic polymer types pollute the soil, the stronger the growth suppression of invasive alien and native plants

This study shows that increased diversity of synthetic polymer types in soil leads to stronger growth suppression of both invasive and native plants, with more pronounced effects on invasive species.

A latitudinal pattern of plant leaf-associated bacterial community assembly

The paper identifies a latitudinal gradient in plant leaf-associated bacterial communities, showing host-driven selection at high latitudes and multiple factors at low latitudes.

Novel tumorigenic FOXM1-PTAFR-PTAF axis revealed by multi-omic profiling in TP53/CDKN2A-double knockout human gastroesophageal junction organoid model

Actin cytoskeleton signaling via MRTF/SRF entrains circadian clock

This study shows that actin cytoskeleton signaling via MRTF/SRF modulates circadian clock entrainment by responding to extracellular matrix cues.

Circadian clock control of MRTF-SRF signaling suppresses beige adipocyte thermogenic recruitment

This study identifies a circadian clock control of MRTF-SRF signaling that suppresses beige adipocyte thermogenic recruitment and maintains metabolic homeostasis.

Tree species and genetic diversity increase productivity via functional diversity and trophic feedbacks

This study shows that both tree species and genetic diversity increase productivity through functional diversity and trophic feedbacks, with genetic diversity effects varying between monocultures and mixtures.

Global Spatial Transcriptome of Macaque Brain at Single-Cell Resolution

The paper creates a 3-D cell type atlas of the monkey brain using single-cell spatial transcriptomics and identifies molecular markers for neocortical layers and subregions.

Histone demethylase UTX regulates glioblastoma progression through affecting periostin expression

This study shows that UTX promotes glioblastoma progression by upregulating periostin expression, and its knockdown inhibits tumor growth and promotes apoptosis.

Integrin signaling via actin cytoskeleton activates MRTF/SRF to entrain circadian clock

This study identifies an integrin-actin cytoskeleton-MRTF/SRF signaling cascade that modulates circadian clock properties by directly regulating core clock genes.

Abundant and rare bacterial taxa structuring differently in sediment and water in thermokarst lakes in the Yellow River Source area, Qinghai-Tibet Plateau

This study compares bacterial communities in sediment and water of thermokarst lakes, finding distinct differences in diversity and community structure, with rare taxa showing stronger environmental structuring.

Undersampling correction methods to control γ-dependence for comparing β-diversity between regions

This study evaluates undersampling correction methods for β-diversity to reduce γ-dependence, finding that diversity accumulation curves outperform null models in removing γ-dependence.

Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball patterned arrays

This study develops Stereo-seq, a high-resolution spatial transcriptomic method, to analyze mouse organogenesis and map developmental disease loci.

Hydraulic diversity stabilizes productivity in a large-scale subtropical tree biodiversity experiment

The paper shows that tree species richness stabilizes forest productivity through increased species asynchrony and hydraulic trait diversity, not community-weighted means.

Sequencing of clinical samples reveals that adaptation keeps establishing during H7N9 virus infection in humans

This study analyzes H7N9 virus genome mutations in human clinical samples to identify potential adaptations during infection.

A valid protective immune response elicited in rhesus macaques by an inactivated vaccine is capable of defending against SARS-CoV-2 infection

This study shows an inactivated SARS-CoV-2 vaccine induces neutralizing antibodies and CTL responses in rhesus macaques, effectively preventing viral replication and lung inflammation.

Species packing and the latitudinal gradient in beta-diversity

The paper tests whether beta-diversity contributes to the latitudinal gradient in species richness by analyzing tree species data across East Asia.

Accurate Diagnosis of Colorectal Cancer Based on Histopathology Images Using Artificial Intelligence

This paper develops an AI tool for colorectal cancer diagnosis using histopathology images, achieving high accuracy and consistency across multiple centers.