Hemopexin Reverses Activation of Lung eIF2a and Decreases Mitochondrial Injury in Chlorine Exposed Mice
S. Matalon, Z. Yu, S. Dubey, I. Ahmad, E. M. Stephens, A. S. Alishlash, A. Meyers, D. Cossar, D. Stewart, E. P. Acosta, K. Kojima, T. Jilling, J. A. Mobley
This study shows that hemopexin reduces acute lung injury and mitochondrial damage in chlorine-exposed mice by reversing eIF2α activation and mtDNA lesions.
bioRxiv · Aug 17, 2023 · PreprintPhysiology