S. Dubey

Hemopexin Reverses Activation of Lung eIF2a and Decreases Mitochondrial Injury in Chlorine Exposed Mice

This study shows that hemopexin reduces acute lung injury and mitochondrial damage in chlorine-exposed mice by reversing eIF2α activation and mtDNA lesions.

Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses

This study compares molecular mechanisms and antiviral targets of Old and New World hantaviruses using human cell models and identifies potential therapeutic compounds.

SARS-CoV-2 variants exhibit differential gut tropism and dysbiosis in Syrian golden hamsters.

This study examines SARS-CoV-2 variants' gut tropism and impact on gut microbiota in Syrian golden hamsters, finding Delta's stronger gastrointestinal preference and greater microbial dysbiosis.

Autoacetylation-mediated phase separation of TIP60 is critical for its functions

This study identifies autoacetylation on lysine 187 as critical for TIP60's phase separation, nuclear localization, and functional interactions.

Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses

This study identifies broad-spectrum antiviral agents effective against multiple RNA virus families, including arboviruses and respiratory pathogens.

Bronco T (Shirisadi kasaya), a polyherbal formulation ameliorates LPS induced septicemia in rats

Bronco T, a polyherbal formulation, improves survival and lung function in LPS-induced septicemia in rats, with effects comparable to pentoxifylline.

The axonal actin-spectrin lattice acts as a tension buffering shock absorber

The paper investigates axon biomechanics and finds that the actin-spectrin lattice functions as a tension buffer by reversibly unfolding spectrin domains to absorb mechanical stress.

Elucidating the active interaction mechanism of phytochemicals withanolide and withanoside derivatives with human serum albumin

This study investigates the binding of withanolide and withanoside derivatives from Withania somnifera with human serum albumin using spectroscopy, docking, and microscopy techniques, showing strong binding interactions.