Author

D. Couto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Savva· 2 shared M. Korach-Andre· 2 shared M. R. Domingues· 2 shared T. Melo· 2 shared X. Li· 2 shared A. M. E. Jones· 1 shared A. P. Macho· 1 shared A. Petriello· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersPhysiology

C. Savva

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular programming in utero modulates hepatic lipid metabolism and adult metabolic risk in obese mother offspring in a sex-specific manner

C. Savva, L. A. Helguero, M. Gonzalez-Granillo, T. Melo, D. Couto, B. Angelin, M. R. Domingues, X. Li, C. Kutter, M. Korach-Andre

The paper examines sex-specific metabolic differences in offspring of obese mothers, showing females have better metabolic outcomes due to more efficient transcriptional and posttranscriptional reprogramming.

bioRxiv · May 26, 2021Physiology

ACTIVATION LOOP PHOSPHORYLATION OF A NON-RD RECEPTOR KINASE INITIATES PLANT INNATE IMMUNE SIGNALING

K. W. Bender, D. Couto, Y. Kadota, A. P. Macho, J. Sklenar, M. Bjornson, A. Petriello, M. Font Farre, B. Schwessinger, V. Ntoukakis, L. Stransfeld, A. M. E. Jones, F. L. Menke, c. zipfel

This study investigates the activation mechanism of a non-RD LRR-RK, showing that phosphorylation of its cytoplasmic domain initiates immune signaling without requiring reciprocal transphosphorylation.

bioRxiv · May 1, 2021Biochemistry

Maternal obesity programs white and brown adipose tissue transcriptome and lipidome in offspring in a sex-dependent manner

C. Savva, L. Helguero, M. Gonzalez-Garnillo, T. Melo, d. couto, B. Buyandelger, S. Gustafsson, J. Liu, M. R. Domingues, X. Li, M. Korach-Andre

This study shows maternal obesity differentially programs gene expression in adipose tissues of male and female offspring, contributing to sex-dependent metabolic complications.

bioRxiv · Feb 8, 2021Cell Biology