Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory
T. Hogan, M. Nowicka, D. Cownden, C. Pearson, A. Yates, B. Seddon
This study investigates how self and environmental antigens influence the development and maintenance of CD4+ T cell memory in mice, showing early environmental exposure shapes memory populations, while later replenishment is environment-independent.
bioRxiv · Nov 19, 2019Immunology