Author

T. Hogan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 3 Research Focus:clustering· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:flow cytometry· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Seddon· 3 shared A. Yates· 2 shared M. Nowicka· 2 shared A. J. Yates· 1 shared C. Pearson· 1 shared C. van Dorp· 1 shared C. Williams· 1 shared D. Cownden· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

B. Seddon

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3 papers

Recent·Most cited

The dynamics and longevity of circulating CD4+ memory T cells depend on cell age and not the chronological age of the host

M. E. Bullock, T. Hogan, C. Williams, S. Morris, M. Nowicka, M. Sharjeel, C. van Dorp, A. J. Yates, B. Seddon

This study shows that memory CD4+ T cell persistence depends on cell age, not host chronological age, using mouse models and mathematical models.

bioRxiv · Oct 16, 2023 · PreprintImmunology

Towards a unified model of naive T cell dynamics across the lifespan

S. Rane, T. Hogan, E. Lee, B. Seddon, A. Yates

This study develops a unified model of naive CD4 and CD8 T cell dynamics across the mouse lifespan, revealing that survival capacity increases with age and that naive CD8 T cells are rapidly lost early in life.

bioRxiv · Jan 7, 2022Immunology

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory

T. Hogan, M. Nowicka, D. Cownden, C. Pearson, A. Yates, B. Seddon

This study investigates how self and environmental antigens influence the development and maintenance of CD4+ T cell memory in mice, showing early environmental exposure shapes memory populations, while later replenishment is environment-independent.

bioRxiv · Nov 19, 2019Immunology