Structural Insights into the BRAF Monomer-to-dimer Transition Mediated by RAS Binding
J. A. Martinez Fiesco, D. E. Durrant, D. K. Morrison, P. Zhang
The paper presents cryo-EM structures of BRAF complexes to elucidate how RAS binding initiates conformational changes leading to dimer formation.
bioRxiv · Sep 30, 2021Biochemistry