D. Frei

Hybridization and a mixture of small and large-effect loci facilitate adaptive radiation

The paper investigates the role of genetic architecture and hybridization in adaptive radiation using Alpine whitefish data, finding both genome-wide shifts and a large-effect locus contribute to diversification.

De novo formation of an early endosome during Rab5 to Rab7 transition

The paper describes a stepwise Rab5 detachment process during endosomal maturation, leading to the formation of a new early endosome.

Invariant chain regulates endosomal fusion and maturation through the SNARE Vti1b

This study identifies Vti1b as a SNARE protein that interacts with invariant chain (Ii) to regulate endosomal fusion and maturation, delaying endosomal maturation for efficient antigen processing.