Author

O. Bakke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Frei· 2 shared A. Kucera· 1 shared A. Margiotta· 1 shared D. Mateus· 1 shared E. M. Inderberg· 1 shared F. M. Skjeldal· 1 shared J. Neefjes· 1 shared J. Thibodeau· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

D. Frei

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Author profile →

3 papers

Recent·Most cited

De novo formation of an early endosome during Rab5 to Rab7 transition

F. M. Skjeldal, L. H. Haugen, D. Mateus, D. Frei, O. Bakke

The paper describes a stepwise Rab5 detachment process during endosomal maturation, leading to the formation of a new early endosome.

bioRxiv · Jul 6, 2020Cell Biology

Invariant chain with an AP3 interacting sorting signal is sorted to late endosomal compartments and may improve MHC class I loading and presentation.

A. Kucera, N. B. Pati, E. M. Inderberg, T. F. Gregers, S. Walchli, O. Bakke

This study modifies the invariant chain (Ii) to enhance MHC class I antigen presentation by replacing sorting signals and adding a peptide epitope, improving T-cell activation.

bioRxiv · May 13, 2020 · PreprintImmunology

Invariant chain regulates endosomal fusion and maturation through the SNARE Vti1b

D. Frei, A. Margiotta, M. Borg Distefano, M. Moulefera, L. Janssen, J. Thibodeau, J. Neefjes, O. Bakke

This study identifies Vti1b as a SNARE protein that interacts with invariant chain (Ii) to regulate endosomal fusion and maturation, delaying endosomal maturation for efficient antigen processing.

bioRxiv · Sep 18, 2019 · PreprintCell Biology