PathologybioRxiv
The P387 Thrombospondin-4 Variant Promotes Accumulation of Macrophages in Atherosclerotic Lesions
S. Muppala, M. T. Rahman, I. Krukovets…·O. Stenina-Adognravi
This study investigates the role of the P387 TSP4 variant in promoting macrophage accumulation in atherosclerotic lesions, finding it enhances macrophage adhesion and inflammation in both mice and humans.