Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors
M. C. Crawford, D. R. Tripu, S. A. Barritt, Y. Jing, D. Gallimore, S. C. Kales, N. V. Bhanu, Y. Xiong, Y. Fang, K. A. T. Butler, C. A. LeClair, N. P. Coussens, A. Simeonov, B. A. Garcia, C. C. Dibble, J. L. Meier
This study compares the biochemical and biological potencies of three EP300/CREBBP acetyltransferase inhibitors and demonstrates their utility in investigating epigenetic mechanisms.
bioRxiv · May 15, 2023Biochemistry