ImmunologybioRxiv
IgA Potentiates NETosis in Response to Viral Infection
H. D. Stacey, D. Golubeva, A. Posca…·M. S. Miller
This study shows that IgA:virus immune complexes enhance NETosis in neutrophils via FcRI engagement, independent of TLRs, and demonstrate NETs' ability to trap and inactivate viruses.
DOI 10.1073/pnas.2101497118