Cell BiologybioRxivPreprint
Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C+/- During Development
S. Shafaattalab, A. Y. LI, Y. Maaref…·G. F. Tibbits
This study investigates the pathogenic mechanisms of the TNNT2 R278C+/- variant in cardiomyocytes using proteomics and functional assays, revealing its impact on cardiac function and arrhythmia.
DOI 10.1101/2023.06.06.542948